Washington University's Maxim Artyomov and colleagues link memory T cells favoring granzyme K over granzyme B to healthier aging in a study in Immunity. The 17-year link to illness and death comes from UK Biobank adults whose cell levels were estimated from blood proteins, so the case for an aging blood test is still indirect.
Reality
- Evidence60
- Adoption
- Not scored
- Hype gap+25
- Incentives35
- Confidence58
Clustering 547 tracing experiments splits the mouse motor cortex into 16 modules
A Basel, FMI and Allen Institute team grouped cortical sites by where their axons end, and found primary and secondary motor cortex both reaching the brainstem and spinal cord directly. The 16-module layout is now in the open BrainGlobe atlas.
Reality
- Evidence58
- Adoption22
- Hype gap+18
- Incentives68
- Confidence55
Where a locus coeruleus neuron sits decides where its norepinephrine goes
In a Nature study from the Allen Institute, the mouse locus coeruleus sorts its output by position, with cells high in the nucleus serving cortex and learning and cells low in it serving the brainstem and spinal cord.
Reality
- Evidence58
- Adoption
- Not scored
- Hype gap+20
- Incentives55
- Confidence60
AI BioDesign promises a database of molecules evolution never made
The Allen Institute, the University of Washington and Fred Hutchinson are building models and databases of designed proteins. David Baker told WIRED the field usually sees that something works before it knows why.
Reality
- Evidence34
- Adoption
- Not scored
- Hype gap+45
- Incentives66
- Confidence52
buildConfirmed2 publishers The MIT-licensed projects stay with the DuckDB Foundation, but the more than 30 people who write them would sit on AWS's payroll. No reporting line has been published.
Reality
- Evidence78
- Adoption79
- Hype gap+18
- Incentives76
- Confidence74