Where mRNA nanoparticles enter the gut steers which organs they reach in mice
Georgia Tech and Emory researchers found the gut site where a lipid-nanoparticle mRNA dose lands, cheek to rectum, changes which organs it reaches in mice. That turns the delivery site into a tool for aiming oral vaccines at lymph nodes or GLP-1 therapy at the pancreas.
Reality
- Evidence52
- Adoption
- Not scored
- Hype gap+28
- Incentives68
- Confidence45
Emory researchers link 5,000 IU a day to better cognitive screening scores in people with mild cognitive impairment and sleep disturbance. The exposure sits above the recommended safety ceiling.
Reality
- Evidence30
- Adoption
- Not scored
- Hype gap+40
- Incentives35
- Confidence65
Portland's worst environmental and health burdens often fall outside 1930s redlined zones
Researchers scoring Portland on more than 100 environmental and health indicators found its worst-off neighborhoods often lie outside 1930s redlined zones. Tree planting or health spending steered only by the old HOLC lines would pass over those places.
Reality
- Evidence45
- Adoption
- Not scored
- Hype gap+15
- Incentives
- Not scored
- Confidence50
Fully air-conditioned schools showed one fifth the learning loss in a July heat review
A systematic review pooled 14 studies tying higher temperatures to lower math, science and reading scores. Its cooling finding compares schools that had air conditioning with schools that did not, so district money is part of what the number measures.
Reality
- Evidence58
- Adoption30
- Hype gap+15
- Incentives30
- Confidence55
NSF NCAR couples its Atlanta heat dataset to a weather model that accounts for buildings
HUMID-Atlanta covers 2010 through 2023 and is publicly available. Whether its building-scale wind and humidity explain heat harm better than thermometer readings is being tested in an NCAR and Emory study of kidney injury.
Reality
- Evidence52
- Adoption28
- Hype gap+18
- Incentives66
- Confidence56
Women's stated job interest followed the advertised gender ratio in Emory's experiments
Psychologists at Emory ran questionnaire experiments with 1,680 US adults recruited on Prolific, and women reported more interest in jobs advertised as having more women, even when the abilities the ads listed were stereotypically male.
Reality
- Evidence45
- Adoption
- Not scored
- Hype gap+30
- Incentives60
- Confidence45
A physician and a veterinary dean want hospitals to ask who is feeding the dog
Their New England Journal of Medicine perspective argues that unasked questions about pet care push patients to delay treatment or go home early, which is plausible and cheap to fix, though the piece carries no estimate of how often it happens.
Reality
- Evidence42
- Adoption8
- Hype gap+18
- Incentives58
- Confidence52
Dead microbes register soil carbon change years before the stock is measurable
An NC State-led team tracked enzymes and living and dead microbial mass under layered regenerative practices in pine and pecan agroforestry, where the biology answers years before a stock measurement could. Calibrating those signals against tonnes is still outstanding.
Reality
- Evidence44
- Adoption
- Not scored
- Hype gap+22
- Incentives58
- Confidence41
Ten daily doses of venetoclax at ART start shrank the intact SIV reservoir in macaques
Emory researchers report in Nature Microbiology that ten days of an approved blood-cancer drug, given as antiretroviral therapy began, left the intact SIV reservoir smaller nine months later. No animal was taken off ART to test rebound.
Reality
- Evidence54
- Adoption12
- Hype gap+22
- Incentives62
- Confidence48
Intimate partner violence recurs across all three homicide types in 115,873 NVDRS deaths
A six-year analysis of US violent death records finds single-, multi-victim and mass homicides differ in who dies and where, yet the same precipitant shows up in all three, which changes where prevention money reaches the most people.
Reality
- Evidence58
- Adoption
- Not scored
- Hype gap+14
- Incentives52
- Confidence55