Maternal cells show up in the brain tissue of 26 of 37 children, sequencing finds
Sami Kanaan's team at the Fred Hutchinson Cancer Center detected maternal cells in 26 of 37 children's brain samples, averaging 2.2 per 100,000 cells. A mosaic brain is a fair inference, but whether the cells affect function or disease is a separate question.
Reality
- Evidence58
- Adoption
- Not scored
- Hype gap+15
- Incentives
- Not scored
- Confidence50
Flu cases in western US states have climbed since early September, weeks ahead of the usual October or November start. Nature reported that researchers are examining an H1N1 mutation, G155E, though the evidence so far is a small Seattle sample and an unreviewed preprint.
Reality
- Evidence55
- Adoption
- Not scored
- Hype gap+20
- Incentives
- Not scored
- Confidence55
AI BioDesign promises a database of molecules evolution never made
The Allen Institute, the University of Washington and Fred Hutchinson are building models and databases of designed proteins. David Baker told WIRED the field usually sees that something works before it knows why.
Reality
- Evidence34
- Adoption
- Not scored
- Hype gap+45
- Incentives66
- Confidence52
Twenty rapid autopsies show bladder cancer metastases mostly seeding other metastases
A University of Washington and Fred Hutch autopsy programme sequenced tumours from 20 people who died of bladder cancer to reconstruct how the disease spread. Plasmacytoid tumours turned out to limit the genomic damage chemotherapy leaves behind.
Reality
- Evidence74
- Adoption
- Not scored
- Hype gap+8
- Incentives55
- Confidence66
Rasonque's approval closed its compassionate-use program before insurers were ready to pay
Revolution Medicines' expanded access program for Rasonque closed immediately on FDA approval, leaving patients still mid-application to wait on insurers whose paperwork moves slower than metastatic pancreatic cancer.
Reality
- Evidence62
- Adoption45
- Hype gap+12
- Incentives55
- Confidence60
Fibromyalgia's genetic trail leads to nerve genes in a 2.5-million-person scan
Twenty-six risk regions, about half of them near genes for nerve cell growth and pain sensitivity, give the condition the biological footing that decades of clinical dismissal lacked, though none of them can diagnose a patient.
Reality
- Evidence62
- Adoption8
- Hype gap+12
- Incentives45
- Confidence56
A rare neuron-like cell may spare dogs a jaw resection
Cornell researchers say single-cell sequencing separates a destructive benign canine oral tumor from its malignant lookalike, and that an ERBB4 inhibitor slowed it in live tissue.
Reality
- Evidence42
- Adoption
- Not scored
- Hype gap+38
- Incentives64
- Confidence34