Peer-reviewed journal publishing research on biomedical devices, materials, and engineering approaches to diagnosis and therapy.
City University of Hong Kong researchers led by Shi Peng mapped RNA in fresh mouse and human tissue with nanoneedles, skipping sequencing and amplification. The team is pitching it for routine pathology on time-sensitive biopsies, and that claim still needs cost and turnaround data.
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An Aarhus-led team reports that injectable photocatalytic nanoparticles gave surviving retinal neurons in blind mice a light input, enough for visual cortex activity and a behavioural change, with the cells left genetically untouched.
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Formulators expected fluid lipid membranes to leak fastest. With the water-soluble neurotoxin tetrodotoxin inside, the most unsaturated liposomes released it slowest and numbed a rat's leg for weeks.
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An Aarhus-led team injected 300-nanometre semiconductor particles into mice with advanced retinitis pigmentosa and recorded light-driven activity in the visual cortex, a route to restoring light sensitivity that does not depend on the patient's mutation.
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Penn State's 20-micrometre shell copies how a fertilised egg hardens its coat, assembling on each islet in solution with a fraction of the polymer of today's capsules. It targets the drug burden that limits islet therapy rather than the supply of donor cells.
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