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Metagenomics

Sequencing DNA taken directly from an environmental sample to identify and characterize the organisms in a community without culturing them individually.

Current stories

scienceOne report1 publisher

Newly found small-genome viruses suggest encapsulins and viruses evolved from each other repeatedly

University of Miami researchers identified previously unknown viruses that bridge viruses and encapsulin compartments in cells, Phys.org reported. The Nature Communications paper reports evidence that the two lineages evolved from one another repeatedly over millions of years. That contests the theory that encapsulins simply descended from viruses.

Publishers:phys.org

Reality

Evidence55
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence45
scienceOne report1 publisher

DNA related to the giant bacterium Epulopiscium turns up in thousands of human gut samples

Researchers searching more than 600,000 microbiomes found DNA related to the giant bacterium Epulopiscium in thousands of human gut samples. The evidence is sequence data only, and Nicola Segata of the University of Trento says the source may be another, unknown bacterium.

Publishers:newscientist.com

Reality

Evidence35
Adoption
Not scored
Hype gap+20
Incentives
Not scored
Confidence40
scienceConfirmed2 publishers

Strain dating suggests gut microbes rare in industrialized people traveled with early humans

Stanford-led researchers find the Hadza and Tsimane share over 1,200 gut bacterial species, about 60% of them rare or absent in industrial guts. For many species, strain split dates match migrations out of Africa and into the Americas, so the missing microbes look like companions handed down over millennia.

Publishers:nature.com phys.org

Reality

Evidence76
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence72
scienceOne report1 publisher

Gutless marine worms swap their indispensable bacterial partners over evolutionary time

Max Planck researchers found gutless marine worms gain and lose essential bacterial partners over time, in a survey of nearly 250 worms from 63 species. The result shows that complete dependence on a microbe can coexist with changing partners across evolutionary time.

Publishers:phys.org

Reality

Evidence50
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence50
scienceOne report1 publisher

Jining team reassembles fragmented microbial gene clusters to rank drug candidates

Researchers at Jining Medical University rebuilt microbial gene clusters broken across contigs and tested six predicted compounds on seven cancer cell lines. The approach ranks leads from microbes no one can culture, though it only prioritizes and the structures and activity still need confirming.

Publishers:phys.org

Reality

Evidence45
Adoption
Not scored
Hype gap+5
Incentives58
Confidence40
scienceOne report1 publisher

Helmholtz profiler Metax flags contamination by how reads spread across a genome

Helmholtz Centre for Infection Research scientists built Metax, a profiler that judges a microbial DNA match by how widely its reads spread across the genome. It targets the false positives current profilers can report, a problem sharpest in low-biomass samples, where host and contaminant DNA swamp the microbial signal.

Publishers:phys.org

Reality

Evidence35
Adoption8
Hype gap+20
Incentives50
Confidence40
scienceOne report1 publisher

Gill DNA once written off as contamination turns up chemosynthesis genes in reef-fish bacteria

ZMT and ICBM researchers rebuilt 70 bacterial genomes from fish-gill DNA once treated as contamination, and the most widespread carry chemosynthesis genes. The study reads gene content only, so whether the microbes fix carbon or help the fish is untested.

Publishers:phys.org

Reality

Evidence50
Adoption
Not scored
Hype gap+15
Incentives40
Confidence55
scienceOne report1 publisher

Age shapes broiler chickens' resistance genes more than antibiotics, probiotics or essential oils

Penn State found age reshaped the resistance genes of 320 broiler chickens far more than antibiotic, probiotic or essential-oil feed did. With the antibiotic diet also flat, the three-week trial cannot show the alternatives reduce resistance.

Publishers:phys.org

Reality

Evidence45
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence40
scienceOne report1 publisher

A Carnegie Mellon lab is coring a 178-acre Pittsburgh steel site for pollutant-eating bacteria

Hazelwood Green's soil carried BTEX for decades before its cleanup. A microbiologist two miles away is sequencing cores from differently contaminated parts of the site to test whether the resident bacteria kept the genes to break those compounds down.

Publishers:phys.org

Reality

Evidence48
Adoption15
Hype gap+30
Incentives62
Confidence55