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Microfluidics

Microfluidics is the science of controlling small fluid volumes in micro-scale channels for diagnostics, synthesis, and cell manipulation.

Current stories

scienceConfirmed2 publishers

Flexible fibers in a Yale microfluidic chip remember past flows as zeros and ones

Yale researchers built a microfluidic chip whose flexible fibers switch between two stable states, so each one can hold a bit of flow history. The Physical Review X study points to all-fluid controllers for soft robots, though the account of it describes only a chip.

Reality

Evidence55
Adoption
Not scored
Hype gap+15
Incentives
Not scored
Confidence65
scienceOne report1 publisher

Honey bee stinger pumps venom with two collapsible pistons, high-speed video shows

Macquarie University researchers used high-speed video to show that a honey bee's 2-millimeter stinger pumps venom with two collapsible pistons. Each lancet carries a valve, and the pair pump in opposite directions to give a continuous flow.

Publishers:phys.org

Reality

Evidence68
Adoption
Not scored
Hype gap+10
Incentives
Not scored
Confidence65
scienceOne report1 publisher

Randomly placed pillars on a chip make tumour cell clusters break apart more often

ISTA and Crick researchers found tumour cell clusters split more often among randomly placed pillars than in an even 9-micrometre grid. The chip lets metastasis research test how tissue geometry around a tumour, apart from its genetics, can push cells to break away.

Publishers:physicsworld.com

Reality

Evidence45
Adoption
Not scored
Hype gap+20
Incentives
Not scored
Confidence50
scienceOne report1 publisher

EHU paper device turns color in about 10 minutes when a drink contains scopolamine

University of the Basque Country researchers led by Lourdes Basabe-Desmonts built a paper test that flags scopolamine in drinks in about 10 minutes. They call it a laboratory-level prototype whose detection ranges and color changes still need optimizing.

Publishers:phys.org

Reality

Evidence35
Adoption2
Hype gap+30
Incentives45
Confidence40
scienceOne report1 publisher

Prior feast-and-famine speeds how fast single E. coli respond to an identical food pulse

A microfluidic experiment held the present identical and varied the past. That design is what separates a reaction from a memory. A mathematical model then placed that memory in ribosomes, though no one watched a ribosome directly.

Reality

Evidence35
Adoption
Not scored
Hype gap+40
Incentives60
Confidence55
scienceOne report1 publisher

One drawn polymer fiber records and doses at several depths of a mouse brain

DTU's mAxialtrode packs a light-guiding core and eight liquid channels into a fiber thinner than half a millimetre. It worked in mice, and its developers say routine clinical use needs much more testing and regulatory approval.

Publishers:sciencedaily.com

Reality

Evidence48
Adoption10
Hype gap+15
Incentives72
Confidence55
scienceOne report1 publisher

CNPEM built a microfluidic chip that gives the spheroid back after the assay

The Brazilian group's platform grows 3D cell models under continuous flow and opens afterward so the tissue can be recovered intact, with plans to offer it to outside labs as shared infrastructure early next year.

Publishers:phys.org

Reality

Evidence55
Adoption
Not scored
Hype gap+28
Incentives60
Confidence52
scienceOne report1 publisher

One chip, several size thresholds: Science Tokyo tunes DLD pillars with heat

A degree at each end of the channel decides which blood fractions come out where. The fixed critical diameter that has defined deterministic lateral displacement becomes a setpoint.

Publishers:phys.org

Reality

Evidence61
Adoption8
Hype gap+12
Incentives58
Confidence54