Topic
High-throughput single-cell gene-expression profiling used to build organism-scale cell atlases.
Sukunaarchaeum, a marine archaeon with 189 protein-coding genes, carries genes for copying its DNA and making proteins but almost none for food or energy. That puts it nearer an independent cell than an organelle, though so far the only evidence is its genome.
Reality
James Zou's agent company read the results of tens of thousands of finished trials and found that drugs aimed at switch-like, cell-type-specific targets reached market about 48% more often. No experiment has tested that yet.
Reality
Bigelow Laboratory's GORG-Dark holds more than 9,600 genomes, each from a single sorted cell, including samples from the Mariana Trench and the Antarctic, and the Cell paper reports widespread genetic potential for chemoautotrophy.
Reality
A Science paper reads gene regulation cell by cell in the human hippocampus and finds embryonic microglia giving way to cells with blood-like inflammatory signatures across a 25-year band of adult life.
Reality
Cornell researchers say single-cell sequencing separates a destructive benign canine oral tumor from its malignant lookalike, and that an ERBB4 inhibitor slowed it in live tissue.
Reality
Junyue Cao read 21 million cells from 14 organs and says aging arrives in discrete stages. If the staging holds, an intervention has a window rather than a dose.
Reality