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Topic

Gene Editing

Techniques such as base editing and prime editing that alter specific DNA sequences, used in research and in developing therapies for inherited disease.

Current stories

productConfirmed2 publishers

Colossal's GenoMorph borrows from more than 70 bird species to pick about 2,300 dodo edit targets

Colossal Biosciences says its GenoMorph platform has found about 2,300 candidate dodo edit targets while working from a single dodo genome. CEO Ben Lamm says the targets still need lab testing, and the platform edits no genes itself.

Perspective Coverage

4 publishers
Builder
Builder 45%
Operator
Operator 25%
Investor
Investor 30%

Reality

Evidence35
Adoption
Not scored
Hype gap+25
Incentives70
Confidence60
investOne report1 publisher

Colossal Biosciences shortlists about 2,300 dodo beak targets with its dodo genome 95% filled

Colossal Biosciences says its GenoMorph AI shortlisted about 2,300 candidate targets for the dodo's beak and that its dodo genome is 95% filled. The company announced no timeframe for hatching a dodo, and the shortlist is still being validated in the lab.

Reality

Evidence35
Adoption
Not scored
Hype gap+30
Incentives60
Confidence50
scienceOne report1 publisher

Type VI retrons need a phage to start making the DNA that switches on their toxin

Gladstone researchers report in Molecular Cell a bacterial antiviral defense, type VI retrons, that works in reverse of known systems. Shipman's lab is working to use retrons to rewrite disease-causing mutations in human cells, but the tests described here used bacteria.

Publishers:phys.org

Reality

Evidence62
Adoption
Not scored
Hype gap+30
Incentives
Not scored
Confidence58
scienceOne report1 publisher

Fused bacterial proteins insert large DNA blocks at a programmed genome site

A team led by microbiologist Joe Peters fused two unrelated bacterial proteins into a compact tool that inserts large DNA blocks at a chosen genome site. It works in bacteria, and the team is still hunting for relatives that work in human or plant cells.

Publishers:phys.org

Reality

Evidence55
Adoption12
Hype gap+30
Incentives70
Confidence35
productOne report1 publisher

Anthropic's Crispr-like find from 950 Claude agents still waits on the wet lab

Anthropic says about 950 Claude agents found an enzyme system reminiscent of Crispr in 21.5 hours, backed so far by one unreviewed lab experiment. Scientists credit the speed of the search, so a lab can budget for faster triage today while the bench works out what the enzyme does.

Publishers:wired.com

Reality

Evidence35
Adoption
Not scored
Hype gap+45
Incentives70
Confidence50
buildConfirmed5 publishers

Anthropic's 950 Claude agents spent 210 million tokens to hand biologists 20 enzyme leads

Anthropic ran about 950 Claude agents for 21 hours on 210 million tokens to cut over 200,000 reverse transcriptases to 20 lab candidates. Human scientists kept the bench work, so lab capacity sets how fast those leads get tested.

Perspective Coverage

5 publishers
Builder
Builder 45%
Operator
Operator 36%
Investor
Investor 19%

Reality

Evidence46
Adoption
Not scored
Hype gap+48
Incentives80
Confidence64
productOne report1 publisher

United Therapeutics launches world's first pig-kidney clinical trial

United Therapeutics is sponsoring the first xenotransplant clinical trial. Its first patient got a 10-edit pig kidney at NYU Langone in November. The longest a gene-edited pig kidney has worked in a person is 271 days, against years or decades for a human donor organ.

Publishers:gizmodo.com

Reality

Evidence52
Adoption31
Hype gap+22
Incentives72
Confidence44
investOne report1 publisher

Anthropic credits Claude with three of the five steps in a gene-editing discovery

Dario Amodei says Claude read the literature and genome data, found something and proposed the experiments, while Anthropic's scientists chose the topic and ran them. He says the finding's function is not yet clear.

Publishers:foxbusiness.com

Reality

Evidence26
Adoption12
Hype gap+44
Incentives76
Confidence44
investOne report1 publisher

S32 leads $140 million round for Basecamp Research's DNA from a million unsequenced species

The Series C values Basecamp Research at about $800 million, roughly 3.6 times everything it has raised, on the strength of a proprietary sequence library and scaling comparisons the company ran internally.

Publishers:techtimes.com

Reality

Evidence30
Adoption15
Hype gap+38
Incentives78
Confidence45
scienceOne report1 publisher

Repair proteins bridged a broken DNA end with the nucleosome still in place

Two Johns Hopkins papers in Nature Communications examined double-strand breaks in DNA still wound on histones. The repair machinery joined the broken ends without stripping that packaging off first.

Publishers:phys.org

Reality

Evidence64
Adoption12
Hype gap+12
Incentives55
Confidence60
investOne report1 publisher

Eight Korean institutions will share 3.26 billion won a year to field-test medical AI agents

Korea's ARPA-H is funding CHAIN, an agentic-AI orchestration programme led by Seoul National University Hospital, with 14.65 billion won through 2030 and a target of 1,000 verified medical agents. Eight institutions take part.

Publishers:en.sedaily.com

Reality

Evidence42
Adoption
Not scored
Hype gap+30
Incentives70
Confidence45